The Parasitic Ulcer Treatment Trial (PUTT) is a multi-center clinical trial investigating whether adding topical corticosteroids to the treatment regimen for Acanthamoeba Keratitis (AK) can improve vision. The study is open to individuals aged 8 and older who are experiencing ocular inflammation after at least one month of anti-amoebic therapy.
The trial is currently recruiting participants at the following locations:
- University of California, San Francisco (UCSF)
- University of Florida, Gainesville
- University of Miami
- University of Illinois, Chicago
- University of Iowa, Iowa City
- Oregon Health and Science University, Portland
- Aravind Eye Hospital, Coimbatore, India
- Federal University of São Paulo, Brazil
- Moorfields Eye Hospital, London, UK
- University of California, Los Angeles (UCLA)
- Johns Hopkins University, Baltimore
- Columbia University, New York
- University of Pennsylvania, Philadelphia
- University of Michigan, Ann Arbor
This study will evaluate the effect of topical corticosteroids vs. placebo on vision, eye pain, and clinical resolution over a period of up to 12 months.
For more information on participation criteria or to inquire about enrolling in the trial, please visit the official trial page:
ClinicalTrials.gov – PUTT Study
This important research is being led by Dr. Jeremy Keenan at the University of California, San Francisco, in collaboration with other renowned institutions, including Moorfields Eye Hospital and Aravind Eye Hospital.
Help us spread the word about this opportunity for patients to potentially benefit from the latest treatment developments in Acanthamoeba Keratitis!
