Our aim is to gather and supply the most important and latest information regarding Acanthamoeba Keratitis in one, easy to access platform. It can be articles, publications, research, clinical trials or tutorials about AK.

By sharing knowledge and information about AK, we encourage all stakeholders to take action in prevention, diagnose and treatment of this serious eye infection.

If you have any questions or information to share, please do not hesitate to contact us.

Basic Information

Medical Community

Contact Lens Users


Prevent Blindness

CDC – Centers for Disease Control and Preventions

AAO – American Acadamy of Ophtalmology

Moorfields Eye Hospital NHS Foundation Trust


Acanthamoeba Keratitis, Pathology, Diagnosis and Treatment

Fanselow N, Sirajuddin N, Yin X-T, Huang AJW, Stuart PM. Acanthamoeba Keratitis, Pathology, Diagnosis and Treatment. Pathogens (2021)

The global epidemiology and clinical diagnosis of Acanthamoeba keratitis

Yuheng Zhang, Xizhan Xu, Zhenyu Wei, Kai Cao, Zijun Zhang, Qingfeng Liang– Science Direct – (2023)

Acanthamoeba keratitis: an increasingly common infectious disease of the cornea

Binod Rayamajhee, Mark DP Willcox, Fiona L Henriquez, Constantinos Petsoglou, Nicole Carnt – The Lancet Microbe – (2021)

Challenges in Acanthamoeba Keratitis: A Review

Giuseppe Varacalli, Antonio Di Zazzo,Tommaso Mori,Thomas H. Dohlman, Sara Spelta, Marco Coassin, and Stefano Bonini, J. Clin. Med. 2021, 10(5), 942; – MDPI (2021)

The rising incidence of Acanthamoeba keratitis: A 7-year nationwide survey and clinical assessment of risk factors and functional outcomes

Anna C Randag, Jeroen van Rooij, Arnoud T van Goor, Samuël Verkerk, Robert P L Wisse, Isabelle E Y Saelens, Remco Stoutenbeek, Bart T H van Dooren, Yanny Y Y Cheng, Cathrien A Eggink – Plos One – (2019)

An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment

Jacob Lorenzo-Morales, Naveed A. Khan, and Julia Walochnik. NCBI (2015)

The rising tide of Acanthamoeba keratitis in Auckland, New Zealand: a 7‐year review of presentation, diagnosis and outcomes

James McKelvie Franzco PhD Moaz Alshiakhi MBChB Mohammed Ziaei FRCOphth Dipika V Patel MRCOphth PhD Charles NJ McGhee FRANZCO DSc (2009–2016)

Acanthamoeba spp. as agents of disease in humans.

Marciano-Cabral F, Cabral G. Clin Microbiol Rev. (2003) 


Novel Map Biopsy Technique to Define the Extent of Infection Before Penetrating Keratoplasty for Acanthamoeba Keratitis

Simpson, Alasdair MBChB, MSc (Hons); Sarode, Deep MBChB (Hons), BMedSci (Hons); Lockington, David FRCOphth, PhD; Ramaesh, Kanna FRCOphth – Cornea –  (2023)

Ultrasensitive and rapid diagnostic tool for detection of Acanthamoeba castellanii

Susanna Haapanen, Maarit S. Patrikainen , Seppo Parkkila – Science Direct (2023)

The role of the calcofluor white staining in the diagnosis of Acanthamoeba keratitis

Elhardt, C., Schweikert, R., Hartmann, L.M. et al. J Ophthal Inflamm Infect 13, 23 (2023)

Outcomes of amoebic, fungal, and bacterial keratitis: A retrospective cohort study

Moe CA, Lalitha P, Prajna NV, Mascarenhas J, Srinivasan M, et al. – PLOS ONE 17 – (2022)

Acanthamoeba Keratitis: A Single-Institution Series of Four Cases With Literature Review

Clarissa Smith, Nida Ashraf, Megan Haghnegahdar, Kenneth Goins, Jessica R. Newman – Cureus – (2022)

Therapeutic Corneal Transplantation in Acanthamoeba Keratitis: Penetrating Versus Lamellar Keratoplasty

Di Zazzo, Antonio MD; Varacalli, Giuseppe MD; De Gregorio, Chiara MD; Coassin, Marco MD, PhD; Bonini, Stefano MD – Cornea– (2022)

Acanthamoeba epitheliopathy: Importance of early diagnosis

Gavin Li, Nakul Shekhawat. American Journal of Ophthalmology Case Reports (2022)

Ocular Hypertension, Glaucoma Frequent Complications of Acanthamoeba Keratitis

Carlene Majorino – Optometry Advisor – (2021)

Confocal microscopy in the diagnosis of acanthamoeba keratitis

Kasparova EA, Marchenko NR, Surnina ZV, Mitichkina TS. Vozmozhnosti konfokal’noi mikroskopii v diagnostike akantamebnogo keratita Vestn Oftalmol. – PMID – (2021)

Therapeutic Corneal Transplantation in Acanthamoeba Keratitis: Penetrating Versus Lamellar Keratoplasty

Antonio Di Zazzo , Giuseppe Varacalli, Chiara De Gregorio, Marco Coassin, Stefano Bonini – Cornea. 2021 Oct 23. Epub ahead of print. PMID (2021)

Voriconazole in the successful management of a case of Acanthamoeba-Cladosporium keratitis

Anita Raghavan, Arjun Velayudhan Nair, Kavitha N, Narendran Venkatapathy and Ram Rammohan – American Journal of Ophthalmology Case Reports – (2021)

Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis – Cross-linking acelerado de colágeno no controle da ceratite por Acanthamoeba avançada

Cartes Cristian, Casas del Valle Marco, Kantor Arturo, Pérez Claudio, Srur Miguel, Raimann Rolf, López Remigio, Traipe Leonidas – Scielo – (2019)

Early Deep Anterior Lamellar Keratoplasty (DALK) for Acanthamoeba Keratitis Poorly Responsive to Medical Treatment

Sarnicola, Enrica MD; Sarnicola, Caterina MD†; Sabatino, Francesco MD; Tosi, Gian Marco MD; Perri, Paolo MD; Sarnicola, Vincenzo MD – Cornea – (2016)

Riboflavin and Ultraviolet Light A Therapy as an Adjuvant Treatment for Medically Refractive Acanthamoeba Keratitis

Yasin A. Khan, Renata T. Kashiwabuchi, Suy Anne Martins, Juan M. Castro-Combs, Sachin Kalyani, Philip Stanley, David Flikier, Ashley Behrens – kalyanieye – (2011)


Warning to holidaymakers over common swimming mistake that triggers nasty eye infections

Eliza Loukou – The US Sun – (2023)

What is Acanthamoeba Keratitis? Sight-threatening eye infection in contact lens wearers

Kate Green – Optimax – (2022)

Acanthamoeba spp. aggregate and encyst on contact lens material increasing resistance to disinfection.

Campolo Allison, Pifer Reed, Walters Rhonda, Thomas Megan, Miller Elise, Harris Valerie, King Jamie, Rice Christopher A., Shannon Paul, Patterson Brian, Crary Monica Frontiers in Microbiology – Volume 13 – Year 2022

Impact of Acanthamoeba Keratitis on the Vision-Related Quality of Life of Contact Lens Wearers

Carnt NA, Man REK, Fenwick EK, Lamoureux EL, Keay LJ – Cornea – (2022)

Contact Lens Care: Prevent Acanthamoeba From Summer Swimming

Atlantic Institute Eye – (2021)