publications

Our goal is to compile and provide the most essential and up-to-date information on Acanthamoeba Keratitis through a user-friendly platform. This includes articles, case studies, publications, research, clinical trials, and tutorials related to AK.

For healthcare professionals, we segment the information into 3 categories: 1.- Diagnosis and Treatment, 2.- Advanced Therapies and 3.- Epidemiology

 

If you have any inquiries or valuable information to share, please feel free to reach out to us.

Basic Information

HCP

Contact Lens User

BASIC INFORMATION

  • Prevent Blindness
  • CDC – Centers for Disease Control and Preventions
  • AAO – American Academy of Opthalmology – EyeWIKI
  • Moorfields Eye Hospital NHS Foundation Trust

HEALTHCARE PROFESSIONAL

Diagnosis and Treatment

  • Case Study: 54 year old man with acute painful redness in his right eye  with photophobia after he slept in his contact lens the previous night. Zachary Reynard, Taher Eleiwa – Eye Meds Now –  (2024)
  • Acanthamoeba epitheliopathy: Importance of early diagnosis. Gavin Li et Al. American Journal of Ophthalmology Case Reports (2022)
  • Diagnosing and monitoring the characteristics of Acanthamoeba keratitis using slit scanning and laser scanning in vivo confocal microscopy. K. Curro-Tafili et al – OPO – (2022)
  • Acanthamoeba Keratitis, Pathology, Diagnosis and Treatment. Fanselow N, et al. Pathogens (2021)
  • An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment. Jacob Lorenzo-Morales et al. NCBI (2015)
  • The rising tide of Acanthamoeba keratitis in Auckland, New Zealand: a 7‐year review of presentation, diagnosis and outcomes. James McKelvie Franzco et al. FRANZCO DSc (2009–2016)
  • Challenges in Acanthamoeba Keratitis: A Review. Giuseppe Varacalli et al., J. Clin. Med. 2021, 10(5), 942; – MDPI (2021)
  • Outcomes of amoebic, fungal, and bacterial keratitis: A retrospective cohort study. Moe CA et al. – PLOS ONE 17 – (2022)
  • Acanthamoeba Keratitis: A Single-Institution Series of Four Cases With Literature Review. Clarissa Smith et al – Cureus – (2022)
  • Confocal microscopy in the diagnosis of acanthamoeba keratitis. Kasparova EA et al. – PMID – (2021)
  • Ocular Hypertension, Glaucoma Frequent Complications of Acanthamoeba Keratitis Carlene Majorino – Optometry Advisor – (2021)

Advance Techniques

  • The Orphan Drug for Acanthamoeba Keratitis (ODAK) Trial: PHMB 0.08% (Polihexanide) and Placebo versus PHMB 0.02% and Propamidine 0.1% John K G Dart et al – Ophtalmology –  (2024)
  • Novel Map Biopsy Technique to Define the Extent of Infection Before Penetrating Keratoplasty for Acanthamoeba Keratitis. Simpson, Alasdair et al – Cornea –  (2023)
  • Ultrasensitive and rapid diagnostic tool for detection of Acanthamoeba castellanii. Susanna Haapanen et al – Science Direct (2023)
  • The role of the calcofluor white staining in the diagnosis of Acanthamoeba keratitis. Elhardt, C. et al. J Ophthal Inflamm Infect 13, 23 (2023)
  • Therapeutic Corneal Transplantation in Acanthamoeba Keratitis: Penetrating Versus Lamellar Keratoplasty. Di Zazzo, Antonio MD et al– Cornea– (2022)
  • Voriconazole in the successful management of a case of Acanthamoeba-Cladosporium keratitis. Anita Raghavan et al – American Journal of Ophthalmology Case Reports – (2021)
  • Systemic Miltefosine as an Adjunct Treatment of Progressive Acanthamoeba Keratitis.  Andrea Naranjo et al – PubMed – (2021)
  • Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis. Cartes Cristian et al – Scielo – (2019)
  • Riboflavin and Ultraviolet Light A Therapy as an Adjuvant Treatment for Medically Refractive Acanthamoeba Keratitis. Yasin A. Khan et al – kalyanieye – (2011)
  • Early Deep Anterior Lamellar Keratoplasty (DALK) for Acanthamoeba Keratitis Poorly Responsive to Medical Treatment. Sarnicola, Enrica MD et al – Cornea – (2016)

Epidemiology

  • Perspectives on the incidence of Acanthamoeba Keratitis: A Systematic Review and Meta-Analysis. Francesco Aiello et al. –  Ophtalmology – (2024)
  • The global epidemiology and clinical diagnosis of Acanthamoeba keratitis. Yuheng Zhang et al.– Science Direct – (2023)
  • Acanthamoeba spp. aggregate and encyst on contact lens material increasing resistance to disinfection. Campolo Allison et al – Microbiology – Volume 13 – (2022)
  • Acanthamoeba keratitis: an increasingly common infectious disease of the cornea. Binod Rayamajhee et al. – The Lancet Microbe – (2021)
  • Acanthamoeba spp. as agents of disease in humans. Marciano-Cabral F et al.  Clin Microbiol Rev. (2003)
  • The rising incidence of Acanthamoeba keratitis: A 7-year nationwide survey and clinical assessment of risk factors and functional outcomes. Anna C Randag et al. – Plos One – (2019)
  • Acanthamoeba keratitis in 194 patients: risk factors for bad outcomes and severe inflammatory complications.  Nicole Carnt  et al – Br J Ophthalmol – (2018)

CONTACT LENS USER

  • Keeping Your Eyes Safe While Swimming and Sunning. Mary Kane – Vision Monday – (2024)
  • Warning to holidaymakers over common swimming mistake that triggers nasty eye infections. Eliza Loukou – The US Sun – (2023)
  • What is Acanthamoeba Keratitis? Sight-threatening eye infection in contact lens wearers. Kate Green – Optimax – (2022)
  • Impact of Acanthamoeba Keratitis on the Vision-Related Quality of Life of Contact Lens Wearers. Carnt NA et al – Cornea – (2022)
  • Contact Lens Care: Prevent Acanthamoeba From Summer Swimming. Atlantic Institute Eye – (2021)